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Those trials compared taking rimonabant (20 milligrams a day) against a placebo. Rimonabant is not yet approved for use in the United States, where it is known as Zimulti. Effect of Rimonabant on Body Weight and the Metabolic Syndrome in Overweight Patients. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee did not recommend approval of rimonabant (Zimulti / Accomplia) to the US FDA. Rimonabant is not yet accustomed for use in the United States, area it is accepted as Zimulti.
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